85/ 100
B
OverallF57/100
Disinfectant Spray Lysol

Lysol · Fabric Protection Sprays

Disinfectant Spray Lysol

B · Low PFAS

Lower concern, but lack of transparency on formulation.

Verdict: Buy with careEstablished disinfectant with known respiratory irritant profile; use as directed, ensure ventilation, avoid skin contact. PFAS transparency gap noted.

Lysol disinfectant spray is a liquid product with no inherent PFAS risk from material. Brand provides no public PFAS disclosure or testing data.

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We flunk more products than we pass. This one earned its grade. How we grade

Material

Aqueous disinfectant solution in spray bottle

Brand disclosure

Brand is silent on PFAS

Lab data

No public lab test

Why this grade

Safe base material

Made from a material with no inherent PFAS use (ceramic, mineral, or natural fiber).

Helps the grade

Category baseline

other is a category where PFAS exposure is more common.

Hurts the grade

No PFAS disclosure

No public statement about PFAS in this product.

Hurts the grade

The full breakdown

What it's made of and why it matters

Lysol disinfectant spray is an aqueous solution typically containing alkyl dimethyl benzyl ammonium saccharinate (quaternary ammonium compound) or similar biocides, plus water, fragrance, and propellant (usually hydrocarbons). The active ingredients kill microbes on hard surfaces; the propellant disperses them as an aerosol. Inhalation of the spray mist and fragrance components is the primary route of concern, especially with prolonged or unventilated use.

The brand's record and disclosure

Reckitt Benckiser (Lysol's parent company) does not publicly disclose full ingredient details beyond EPA-registered active ingredients. The brand has faced no major recalls or safety warnings specific to Lysol spray in recent years, but the company has been slow to adopt transparent PFAS disclosure practices across its product range. Lysol products are EPA-registered disinfectants, which means active ingredients have undergone safety review, though this does not cover all inert ingredients or long-term inhalation risk.

How it compares in its category

Lysol is a mainstream, widely used disinfectant; competitors include Clorox, Microban, and plant-based alternatives. Unlike bleach-based sprays, Lysol does not produce chlorine gas, reducing acute chemical injury risk. However, quaternary ammonium sprays (including Lysol) carry a consistent respiratory irritation profile similar to category peers. Plant-based or vinegar-based alternatives pose lower inhalation risk but may be less effective against certain pathogens.

If you buy it

Always spray in well-ventilated areas; avoid inhaling mist directly and do not spray toward face or breathing zones. Keep away from children and pets during and after application. Do not mix with other cleaners, especially bleach or ammonia, as this creates toxic gas. Wipe down surfaces after disinfection to reduce residue and ongoing off-gassing; do not use on food-contact surfaces without thorough rinsing.

Beyond PFAS: other things we checked

Established hazard classes for this product type, assessed from public information. These never change the PFAS grade; a Likely flag caps the Verdict at “Buy with care.”

Reported

Respiratory irritation from spray inhalation

Quaternary ammonium compounds and fragrance volatiles in aerosol form are documented respiratory irritants. Prolonged or poorly ventilated use may trigger coughing, wheezing, or asthma exacerbation, especially in sensitive individuals or children.

Possible

Fragrance allergens and sensitizers

Lysol formulations contain undisclosed fragrance blends; specific allergen components are not publicly listed. Repeated inhalation or skin contact in sensitive individuals may cause contact dermatitis or asthmatic response.

Reported

Skin and eye irritation on direct contact

Quaternary ammonium active ingredients and preservatives can cause chemical burns or conjunctivitis if sprayed directly on skin or eyes. Product labeling carries standard warnings for this hazard.

Possible

Propellant-related inhalation risk

Hydrocarbon propellants used in aerosol formulations carry low but documented risk of central nervous system effects with excessive or intentional inhalation. Normal use under ventilation poses minimal risk.

None known

Formaldehyde releasers or preservatives

No public data suggests Lysol spray contains formaldehyde releasers; however, full preservation system is not disclosed, so presence cannot be ruled out entirely without manufacturer confirmation.

What we don’t know

This grade is a model-based estimate from public materials, coatings, and brand disclosure at 72% confidence. It is not a lab result.

No independent PFAS lab test is on record for this exact product. A lab test could move the score in either direction.

The brand has not made a specific, verifiable PFAS-free statement, so part of this score reflects that missing disclosure rather than a confirmed material.

Formulations and coatings change between production runs. Always check the current label before buying.

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More fabric protection sprays grades

How we score: every product runs through the same public 0–100 rubric based on materials, coatings, brand disclosure, lab findings, and recalls. See the full methodology → Spotted a mistake? Report an error.